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Aurora Kinase Inhibitor II
4-(4′-Benzamidoanilino)-6,7-dimethoxyquinazoline, Aurora Kinase Inhibitor II
A cell-permeable anilinoquinazoline compound that acts as a potent, selective, and ATP-competitive inhibitor of Aurora kinases (IC50 = 310 nM and 240 nM for Aurora A and B, respectively, 1.25 µM in MCF7 cells). Due to its limited aqueous solubility and high serum binding property, it is recommended for in vitro, but not in vivo, use.
产品信息
Form Yellow solid
Molar mass 400.4
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥90% by HPLC
Solubility DMSO
Chemical formula C23H20N4O3
CAS number 331770-21-9
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |