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ASK1, GST-Fusion, Human, Recombinant, S. frugiperda
This product has been discontinued.
Recombinant, human ASK1 (accession no. NM_005923), consisting of amino acids 649-946, fused at the N-terminus to GST and expressed in S. frugiperda insect cells using a baculovirus expression system. ASK1, also known as MAPKKK5, activates MKK3, MKK4 (SEK1), and MKK6, is a serine/threonine kinase that is activated in response to TNFα. It plays a central role in stress-induced apoptosis; overexpression of ASK1 induces apoptotic cell death. The active kinase is useful in the study of ASK1 activity regulation and inhibitor screening.
产品信息
Form Liquid
Formulation In 150 mM NaCl, 50 mM Tris-HCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol, pH 7.5.
Molar mass 60000
Avoid freeze/thaw 是的
Specific activity ≥95 nmol/min/mg
Unit definition Kinase activity is measured as the molar amount of phosphate incorporated into MBP at 30°C using a final concentration of 50 µM ATP.
Purity ≥90% by SDS-PAGE
商店和运输信息
Storage ≤ -70°C
Ship Dry Ice Only
Standard Handling |