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分子生化试剂 >> 生化试剂 |
APICIDIN, FUSARIUM SP.
产品编号: |
178276-5MG
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产品名称:
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APICIDIN, FUSARIUM SP. .0 订购此产品 |
供应商:
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Merck |
规格: |
*** |
目录价: |
3,335.00 |
库存状态: |
3周到货 |
CAS编号:
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应用范围: |
生化实验 |
种属来源: |
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相关信息: |
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Apicidin, Fusarium sp.
cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxytryptophan)-L-isoleucyl-D-pipecolinyl], HDAC Inhibitor XI
A potent, cell-permeable inhibitor of histone deacetylase (IC50= 700 pM for parasitic histone deactetylase) that also exibits antiprotozoal and potential anti-malarial properties. Inhibits HeLa cell proliferation (IC50= 50-100 nM) and induces the transcriptional activation of p21 (WAF1). Also prevents H-ras-induced invasive phenotype of MCF10A cells possibly by down-regulating MMP-2.
产品信息
Form Off-white solid
Primary Target histine deacetylase
Primary Target IC50 700 pM
Secondary target HeLa (IC50 = 50-100 nM)
Molar mass 623.8
Protect from Light 是的
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥95% by HPLC
Solubility EtOH and DMSO
Chemical formula C34H49N5O6
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Ship Ambient Temperature Only
Highly Toxic
安全标示
S Phrase S: 22-26-36/37/39-45
Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
R Phrase R: 26/27/28
Very toxic by inhalation, in contact with skin and if swallowed. |
保存条件: |
-20°C |
说明书地址: |
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