AMINOPEPTIDASE N, RAT

Aminopeptidase N, Rat
APN/CD13, aminopeptidase N
Native aminopeptidase N purified from rat renal brush-border membranes and cleaved with papain to produce soluble enzyme. A single-chain, integral membrane protease that, functions with broad specificity to remove N-terminal amino acids from peptides. It has been reported that levels of aminopeptidase N are elevated in cancer subjects and correlate with tumor load, and thus, the enzyme is believed to play a role in angiogenesis.
产品信息
Form  Liquid
Formulation  In 200 mM NaCl, 50 mM Tris-HCl, pH 8.0.
Molar mass  150000
Avoid freeze/thaw  是的
Specific activity  ≥100 units/mg protein
Unit definition  One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol L-Leu-pNA per min at 37°C, pH 7.2
Purity  ≥90% by SDS-PAGE
EC number  3.4.11.2
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling