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Luciferase Inhibitor II
4-(1,3-Benzothiazol-2-yl)-N,N-dimethylaniline
A 2-arylbenzothiazole compound that acts as an inhibitor against the ATP-dependent Photinus pyralis (lucPpy) and Photuris pennsylvanica (lucPpe) luciferase activity (IC50 = 0.2 and 0.32 µM, respectively, with 10 µM ATP, 10 µM luciferin, and 10 nM respective enzyme). Unlike Luciferase Inhibitor I (Cat. No. 119113), Luciferase Inhibitor II is competitive with respect to luciferin and exhibits reduced potency against lucPpe-based commercial luciferase-luciferin formulations with high luciferin concentration (IC50 = 10 µM against Promega's Kinase-Glo®; ineffective against Kinase-Glo® Plus and Kinase-Glo® Max; at a 3-fold formulation dilution and 6.77 µM ATP).
产品信息
Form Pale green solid
Molar mass 254.4
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO or EtOH
Chemical formula C15H14N2S
CAS number 10205-56-8
Declaration Marketed by Promega Corp. under the registered trademarks.
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Harmful
安全标示
S Phrase S: 22-26-36
Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
R Phrase R: 22
Harmful if swallowed. |