ADP-HPD, DIHYDRATE, AMMONIUM

ADP-HPD, Dihydrate, Ammonium Salt
Adenosine 5′-diphosphate (Hydroxymethyl)pyrrolidinediol, NH4
An amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM). Does not affect the activities of either poly(ADP-ribose) polymerase (PARP) or NAD:arginine mono(ADP-ribosyl)-transferase A even at 1 mM concentration. Also acts as an inhibitor of NAD glycohydrolase from Bungarus fasciatus venom at much higher concentrations (IC50 = 260 µM). Note: 1 set = 5 x 60 µg. Note: 1 set = 5 x 60 µg
产品信息
Form  White lyophilized solid
Primary Target  PARG
Primary Target IC50  120 nM
Secondary target  NAD glycohydrolase from Bungarus fasciatus venom (IC50 = 260 µM)
Molar mass  595.4
Protect from Light  是的
Hygrocopic  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  H2O
Chemical formula  C15H23N6O12P2 · NH4 · 2H2O
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling