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Adenosine 3′,5′-cyclic Monophosphorothioate, 2′-O-Monobutyryl-, Rp-Isomer, Sodium Salt
Rp-MB-cAMPS, Na, PKA Inhibitor X
This product has been discontinued.
A cell-permeable, metabolically-stable precursor of Rp-cAMPS (Cat. No. 116814) that acts as a competitive inhibitor of protein kinase A type I and II. During metabolic activation by esterases, the inhibitor and butyrate are released. Reported to inhibit glucose-induced proliferation of the pancreatic β-cell line, INS-1. More lipophilic and cell-permeable than Rp-cAMPS. Note: 5 µmol = 2.19 mg.
产品信息
Form Lyophilized
Primary Target PKA1, PKA2
Secondary target PI3K (IC50 = 83 µM)
Molar mass 437.3
Hygrocopic 是的
Cell permeable 是的
ATP Competitive 是的
Purity ≥98% by HPLC
Solubility H2O
Chemical formula C14H17N5O6PS · Na
CAS number 152218-23-0
Declaration Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |