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  您现在的位置:产品中心 >> 细胞生物学 >> 凋亡诱导剂

ACTINOMYCIN D, STREPTOMYCES SP.

产品编号: 114666-1SET     查看说明书
产品名称: ACTINOMYCIN D, STREPTOMYCES SP.  .0   订购此产品 
供应商: Merck
规格: 1SET
目录价: 2,679.00
库存状态: 3周到货
CAS编号:
应用范围: 细胞凋亡诱导
种属来源:
相关信息:

Anti-neoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. At higher concentrations, DNA polymerase is inhibited. Also acts as a competitive inhibitor of serine proteases. Inhibits cell growth and colony formation in synchronized HeLa cells. Induces apoptosis in many cell lines. However, actinomycin D has also been shown to suppress etoposide-induced apoptosis in PC12 cells. Note: 1 set = 20 x 200 µg. Stability: heat resistant and stable between pH 2 and 11. Decomposed by strong acids and bases.
Form  Red crystalline solid 
Primary Target  serine proteases 
Secondary target  cell growth and colony formation in synchronized HeLa cells 
Protect from Light  是的 
Hygrocopic  是的 
Purity  ≥98% by HPLC 
Chemical formula  C62H86N12O16 
RTECS  AU1575000 
CAS number  50-76-0 
Merck USA index  14, 2800 
Storage  +2°C to +8°C 
Ship  Ambient Temperature Only
Highly Toxic & Carcinogenic / Teratogenic 
凋亡作为一种正常的细胞生物学行为,其研究需要一系列严格的实验程序,这可以通过多种诱导剂刺激细胞膜受体或激活线粒体调亡途径来诱导细胞的凋亡。

保存条件: 原厂要求
说明书地址: 点击查看详细
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