Anti-neoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. At higher concentrations, DNA polymerase is inhibited. Also acts as a competitive inhibitor of serine proteases. Inhibits cell growth and colony formation in synchronized HeLa cells. Induces apoptosis in many cell lines. However, actinomycin D has also been shown to suppress etoposide-induced apoptosis in PC12 cells. Note: 1 set = 20 x 200 µg. Stability: heat resistant and stable between pH 2 and 11. Decomposed by strong acids and bases. Form Red crystalline solid Primary Target serine proteases Secondary target cell growth and colony formation in synchronized HeLa cells Protect from Light 是的 Hygrocopic 是的 Purity ≥98% by HPLC Chemical formula C62H86N12O16 RTECS AU1575000 CAS number 50-76-0 Merck USA index 14, 2800 Storage +2°C to +8°C Ship Ambient Temperature Only Highly Toxic & Carcinogenic / Teratogenic 凋亡作为一种正常的细胞生物学行为，其研究需要一系列严格的实验程序，这可以通过多种诱导剂刺激细胞膜受体或激活线粒体调亡途径来诱导细胞的凋亡。