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Acridine Orange
AO, 3,6-bis(Dimethylamino)acridine, HCl
A cell-permeable, cationic fluorescent dye that interacts with DNA and RNA by intercalation or electrostatic attractions. When bound to DNA, it is spectrally very similar to fluorescein, with an excitation maximum at 502 nm and an emission maximum at 525 nm. Upon association with RNA, the excitation maximum shifts to 460 nm and the emission maximum shifts to 650 nm (red). Often used to measure single- and double-stranded DNA and RNA in the diagnosis, classification, and prognosis of many neoplasms. A very versatile fluorescent stain used in histochemistry and cytochemistry that can be used to provide information about the in situ content, molecular structure, and conformation of many nucleic acid-containing cell constituents.
产品信息
Form Burnt-orange solid
Molar mass 301.8
Protect from Light 是的
Hygrocopic 是的
Purity ≥98% by HPLC
Solubility DMF, EtOH, or H2O
Chemical formula C17H20ClN3
RTECS AR7601000
CAS number 65-61-2
商店和运输信息
Storage +15°C to +30°C
Ship Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic
安全标示
S Phrase S: 36
Wear suitable protective clothing.
R Phrase R: 20/21/22-40
Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect. |