D-ERYTHRO-SPHINGOSINE, N-ACETYL-

D-erythro-Sphingosine, N-Acetyl-
C2 Ceramide
Biologically active, cell-permeable, non-physiological ceramide analog. Inhibits cell growth and induces apoptosis in HL-60 cells. Induces intranucleosomal DNA fragmentation. An activator of heterotrimeric protein phosphatase 2A (PP2A). Stimulates a cytosolic serine/threonine protein phosphatase in T9 cells at concentrations as low as 100 nM. Activates stress activated protein kinase (SAPK) in HL-60 human promyelocytic cells.
产品信息
Form  White to off-white solid
Molar mass  341.5
Purity  ≥98% by TLC
Solubility  DMSO or EtOH
Chemical formula  C20H39NO3
CAS number  3102-57-6
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Irritant
安全标示
S Phrase  S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
R Phrase  R: 36/37/38
Irritating to eyes, respiratory system and skin.