AACOCF3 Arachidonyltrifluoromethyl Ketone, cPLA2α Inhibitor II A cell-permeable trifluoromethyl ketone analog of arachidonic acid. Potent and selective slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2 (cPLA2; IC50 = ~20 µM). Specific inhibition of cPLA2 activity by AACOCF3 partially inhibits TNF-induced apoptosis without inhibition of caspase activity. Causes a significant diminution in thromboxane B2 production in thrombin-stimulated platelets. Also inhibits platelet aggregation in response to collagen and arachidonic acid. 产品信息 Form Clear yellow oil Primary Target cPLA2 Primary Target IC50 20 µM Molar mass 356.5 Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥97% by TLC Solubility DMSO or EtOH Chemical formula C21H31F3O CAS number 149301-79-1 商店和运输信息 Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Storage ≤ -70°C Ship Dry Ice Only Flammable 安全标示 S Phrase S: 16-7 Keep away from sources of ignition - No Smoking. Keep container tightly closed. R Phrase R: 11 Highly flammable.