A23187, FREE ACID, S. CHARTREUSENSIS

A23187, Free Acid, Streptomyces chartreusensis
A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against Gram-positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, A23187 has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.
其他选项
100107  A23187, 4-Bromo-
100106  A23187, Mixed Calcium-Magnesium Salt
产品信息
Form  White solid
Molar mass  523.6
Protect from Light  是的
Purity  ≥98% by TLC
Solubility  DMSO or MeOH
Chemical formula  C29H37N3O6
RTECS  DM4676000
CAS number  52665-69-7
Merck USA index 14, 1639
商店和运输信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Harmful
安全标示
S Phrase  S: 26-36/37/39
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
R Phrase  R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed.