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7-Aminoactinomycin D (7-AAD)
描述
7-aminoactinomycin D (7-AAD) is a fluorescent intercalator that undergoes a spectral shift upon association with DNA. 7-AAD/DNA complexes can be excited by the 488 nm laser and has an emission maxima of 647 nm, making this nucleic acid stain useful for multicolor fluorescence microscopy and flow cytometry. 7-AAD appears to be generally excluded from live cells, but can be used with cells that have been fixed and permeabilized. 7-AAD has been used for cell cycle analysis by flow cytometry. 7-AAD also binds selectively to GC regions of DNA yielding a distinct banding pattern in polytene chromosomes and chromatin for use in chromosome banding studies.
Color: Red
Platform: Flow Cytometer,
Fluorescence Microscope
Product Size: 1 mg
Detection Method: Fluorescent
Cell Permeability: Cell-Impermeant
Sub-Cellular Localization: Nucleic Acids,
Nucleus
Shipping Condition: Room Temperature
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
化学结构
7-aminoactinomycin D
分子式
C62H87N13O16
分子量
1270.45
CAS名称/编号
Actinomycin D, 7-amino-/ 7240-37-1 |