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Claudin-4 Mouse Monoclonal Antibody (clone 3E2C1), Alexa Fluor® 594 Conjugate
Monoclonal antibody conjugated to Alexa Fluor® 594, and specific to Human , Rat , Canine and Mouse . This antibody is validated for use in WB, ICC/IF and ELISA. Claudin-4 is encoded by the CLDN4, also known as CLDN4, claudin 4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R, Clostridium perfringens enterotoxin receptor 1, Williams-Beuren syndrome chromosomal region 8 protein. Initialy only transmembrane protein known to be associated with tight junctions was occludin, an ~65 kDa protein with four transmembrane domains. Despite widespread expectation, a critical structural role for occludin in TJ strands was ruled out by the observation of apparently normal tight junctions formed between cells disrupted at both occludin alleles.1 A closer examination of isolated tight junctions uncovered two related ~22 kDa, four-transmembrane domain proteins, claudin-1 and claudin-2, with no similarity to occludin. In contrast to occludin, which induces only a small number of short strands at cell-cell
Reactivity: Human,
Mouse,
Rat,
Canine
Validated Application: Western Blot,
Immunofluorescence,
ELISA,
Immunocytochemistry
Host: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Clone ID: 3E2C1
Antibody Fragment: Whole Antibody
Target Gene: Claudin-4
Gene ID: 1364
Label or Dye: Alexa Fluor® 594
Excitation⁄Emission (nm): 590⁄617
Excitation Class: Visible
Emission Class: Visible
Purification: Purified
Concentration: 0.5 mg⁄ml
Color: Red
Form: Liquid
Neutralizing Antibody: No
Platform: Fluorescence Microscope
Product Size: 100 µg
Quantity: 1
Volume: 200 µl
Shipping Condition: Wet Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store reagents at 2-8°C. |