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MuRF1 (rat), (recombinant) (GST-tag)
Product Specification
Alternative Name: TRIM63, Tripartite motif-containing protein 63, E3 Ubiquitin-protein ligase TRIM63
MW: ~67kDa
Source: Produced in E. coli BL21 (λDE3).
UniProt ID: Q91Z63
Formulation: Liquid. In 50mM TRIS, pH 7.5, containing 150mM NaCl and 1mM DTT.
Purity: ≥95% (SDS-PAGE)
Purity Detail: Purified by affinity chromatography.
Biological Activity: Recombinant GST-MuRF1 is competent for both auto-ubiquitinylation and ubiquitinylation of substrate proteins in vitro.
Application: 1. Muscle atrophy studies - role of ubiquitinylation.
2. In vitro generation of ubiquitinylated muscle atrophy pathway components.
3. Investigation of MuRF1’s role in muscle wasting process.
4. Control ubiquitin E3 ligase for auto-ubiquitinylation reactions.
Short Term Storage: -80°C
Long Term Storage: -80°C
Use/Stability: Stable for at least 12 months after receipt when stored at -80°C. |