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Mycophenolate mofetil (CellCept) is an immunosuppressant prodrug of mycophenolic acid, a fermentation product of Penicillium brevicompactum. Immunosuppression occurs via inhibition of type II inosine-5’-monophosphate dehydrogenase, depleting guanosine preferentially in T and B lymphocytes. In addition, mycophenolic acid displays anti-inflammatory activity by preventing NO production specifically from iNOS and by blocking glycosylation and expression of adhesion molecules and therefore recruitment of lymphocytes and monocytes to sites of inflammation.
Product Specification
Formula:C23H31NO7
MW:433.5
Source:Isolated from Penicillium brevicompactum.
CAS:128794-94-5
Purity:≥99% (TLC)
Appearance:White to off-white solid.
Solubility:Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml, warm).
Long Term Storage:Ambient
Use/Stability:Stable for at least 1 year after receipt when stored at +20°C. Solutions can be stored for up to 3 months at -20°C. |