|
产品参数：
Formula: C30H28N6O6S4
MW: 696.9
Source: Isolated from Chaetomium sp-
CAS: 28097-03-2
Purity: ≥ 98% (TLC)
Appearance: White to off-white solid.
Hazard: HARMFUL.
Solubility: Soluble in DMSO (25mg/ml), 100% ethanol (25mg/ml), dimethyl formamide or methanol. Poorly souble in water.
Long Term Storage: -20°C
Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
产品说明：
可替代产品：ALX-380-242
Chaetocin, an antitumor antibiotic, is a thiodioxopiperazine natural product produced by Chaetomium species. Specific inhibitor of the lysine-specific methyltransferase SU (VAR)3-9 both in vitro and in vivo. It displays potent antimyeloma activity in IL-6-dependent myeloma cell lines. Its antimyeloma activity appears to be due to induction of oxidative stress and consequent apoptosis. |