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Novel DNA topoisomerase I inhibitor. Unlike camptothecin, β-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1.
Product Specification
Formula:C15H14O3
MW:242.4
CAS:4707-32-8
Purity:98%
Appearance:Orange solid.
Long Term Storage:-20°C |