Endogenous agonist for the nuclear receptor LXR. Important metabolite of cholesterol in the brain. Displays neurotoxic effects on human neuroblastoma cells. Cerebrospinal fluid concentrations of 24(S)-hydroxycholesterol are increased in patients with Alzheimer’s disease and mild cognitive impairment. Product Specification Formula:C27H46O2 MW:402.7 CAS:474-73-7 Purity:≥98% (TLC) Solubility:Soluble in ethanol (10mg/ml) or DMSO (10mg/ml - requires warming to ~40°C). Long Term Storage:-20°C Use/Stability:Store solutions at -20°C for up to 3 months.
