Mevastatin inhibits isoprenoid biosynthesis by inhibition of HMG-CoA reductase (Ki for acid form is 1 nM) and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. It causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases. Product Specification Alternative Name:Compactin Formula:C23H34O5 MW:390.5 CAS:73573-88-3 Purity:≥95% Appearance:White solid. Solubility:Soluble in DMSO (20mg/ml) or 100% ethanol (25mg/ml). Long Term Storage:-20°C