Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=30 nM) and in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=35.8 µM and 67 µM respectively). α-Hydroxyfarnesylphosphonic acid inhibited (1 µM) Ras processing in Ha-ras-transformed NIH 3T3 fibroblasts. Product Specification Formula:C15H27O4P MW:302.4 CAS:140633-12-1 Purity:≥96% (TLC) Appearance:Liquid. 1mg dissolved in 500μl ethanol. Long Term Storage:-20°C Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Handling:Do not evaporate to dryness. Compound decomposes out of solution.