N-Oleoy-L-serine was isolated from mouse brain and trabecular bone and was determined to be the L-isomer. It was shown to promote the growth and proliferation of MC3T3 E1 osteoblasts at 10-11M via a pertusis toxin-sensitive mechanism and transiently induced ERK1/2 phosphorylation. It inhibited osteoclast formation in vitro and in an ovariectomy-induced bone loss model, it induced complete rescue after 12 weeks (5mg/kg). Product Specification Purity:98% Long Term Storage:-20°C