N-Arachidonoyl-L-serine is an endocannabinoid isolated from bovine brain. It binds only very weakly to cannabinoid CB1 and CB2 receptors as well as vannilloid TRPV1 receptors. However, it produces endothelium-dependent vasodilation in rat isolated mesenteric arteries and abdominal aorta. It also suppresses LPS-induced TNFα production in a murine macrophage cell line and in mice. Its biological profile closely parallels that of abnormal cannabidiol an agonist at a putative novel cannabinoid-like receptor. Thus N-arachidonoyl-L-serine may be an endogenous agonist for this receptor. Product Specification Formula:C23H37NO4 MW:391.5 CAS:187224-29-9 Purity:≥98% (TLC) Appearance:Colorless oil. Solubility:Soluble in DMSO (4mg/ml) or dimethyl formamide; sparingly soluble in water. Long Term Storage:-80°C