Endogenous anandamide-like compound. Lacks affinity for CB1 receptors (Ki>10µM), TRPV1 (EC50>10µM) and anandamide uptake (IC50>50µM), but inhibits fatty acid amide hydrolase (FAAH) (IC50=8.5µM-50µM, depending on cell type and species). Displays anti-inflammatory and analgesic activity. Identified as an insulin secretagogue in a primary β-cell-based functional assay. Represents a new class of "lipoamino acids".
Product Specification
Formula:C22H35NO3
MW:361.5
CAS:179113-91-8
Purity:≥98% (TLC)
Appearance:White waxy solid.
Solubility:Soluble in DMSO or 100% ethanol. 2mg/ml soluble in PBS (pH 7.2).
Long Term Storage:-20°C
Handling:Protect from air. |