Ac-IETD-pNA Caspase and granzyme substrate Replaces Prod. #: BML-P431 Chromogenic substrate for caspase-6, -8 and granzyme B. Also a substrate for caspase-10. Similar to Ac-IETD-AMC and Ac-IETD-AFC but cleavage is monitored colorimetrically by absorbance at 405 nm. Product Specification Alternative Name: Caspase-8 substrate (chromogenic), Granzyme B substrate (chromogenic) Sequence: Ac-Ile-Glu-Thr-Asp-pNA (pNA=p-Nitroaniline) Formula: C27H38N6O12 MW: 638.6 Formulation: Lyophilized. Peptide Content: 70-90% Purity: 98% (HPLC) Appearance: White to yellow powder. Solubility: Soluble in DMSO. Dilute with buffer, pH 7.0-7.5. Long Term Storage: -20°C Handling: Keep cool and dry. |