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Z-YVAD-AFC
Caspase-1 substrate
Replaces Prod. #: BML-P406
Fluorogenic substrate for caspase-1. AFC has an excitation maximum of 400nm and an emission maximum of 505nm. This product is similar to Ac-YVAD-AMC, Prod. No. ALX-260-024, but the AFC fluorophore has a greater Stokes' shift upon cleavage and the N-terminal is blocked by a benzyloxycarbonyl moiety, which increases cell permeability.
Product Specification
Alternative Name: Caspase-1 substrate (fluorogenic)
Sequence: Z-Tyr-Val-Ala-Asp-AFC (AFC = 7-Amido-4-trifluoromethylcoumari
Formula: C39H40N5O11F3
MW: 811.8
Purity: ≥95% (HPLC).
Single spot (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO, DMF or methanol; insoluble in water.
Long Term Storage: -20°C
Use/Stability: DMF or DMSO stock solution highly stable at -20°C.
Handling: Protect from light. |