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Z-Asp-2,6-dichlorobenzoyloxymethylketone
Caspase inhibitor
Replaces Prod. #: BML-P415
Irreversible, cell permeable broad-spectrum caspase inhibitor.
Caspase-3 IC50: 1,1µM
Caspase-6 IC50: 4,1µM
Less effective on the inhibition of caspase-1- and 8-like activities.
Inhibits hypoxia-induced apoptosis in neuroblastoma cells.
Product Specification
Alternative Name: Caspase family inhibitor, Z-Asp-CH2-DCB, Z-L-Asp-a-[2,6-(dichlorobenzoyl)oxy]methane
Formula: C20H17Cl2NO7
MW: 454.3
CAS: 153088-73-4
Purity: ≥98% (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in methanol (50mg/ml) or DMSO.
Long Term Storage: -20°C
Use/Stability: Stock solutions should be divided into aliquots and stored at -20°C.
Handling: Keep cool and dry. |