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E-64
Protease inhibitor
Replaces Prod. #: BML-PI105
Irreversible inhibitor of cysteine proteinases like papain, calpain, cathepsin B, L and H. Acts by forming a thioether bond with the thiol of the active cysteine. Does not inhibit serine proteinases. Inhibits degradation of autophagic cargo in autophagolysosomes.
Product Specification
Alternative Name: N-[N-(L-3-trans-Carboxyoxirane-2-carbonyl]-L-leucyl)-agmatine, L-trans-Epoxysuccinyl-leucylamide-(4-guanido)-butane
Formula: C15H27N5O5 . 0.5 H20
MW: 357.4
Source: Synthetic.
CAS: 66701-25-5
Purity: ≥98%
Appearance: White to off-white solid.
Solubility: Soluble in DMSO or water (4mg/ml).
Long Term Storage: -20°C
Handling: Protect from light. |