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Caveolin-1 scaffolding domain peptide
Cell permeable eNOS blocker
Cell permeable peptide that blocks eNOS (NOS III) activity and cellular nitric oxide (NO) release in vitro and reduces inflammation and tumorigenesis in vivo. Caveolin-1 interacts with several lipid-modified signalling ligands, such as EGFR, eNOS, G-protein α-subunits, PKCα, H-Ras, and Src, via the C1-SD82-101 sequence.
Product Specification
Alternative Name: Cavtratin, AP-Cav, Pen-C1-SD
Sequence: H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Asp-Gly-Ile-Trp-Lys-Ala-Ser-Phe-Thr-Thr-Phe-Thr-Val-Thr-Lys-Tyr-Trp-Phe-Tyr-Arg-OH
Formula: C228H335N61O49S
MW: 4746.6
Purity: ≥97% (HPLC)
Appearance: White lyophilized powder.
Solubility: Soluble in DMSO or acetonitrile:water (50:50).
Long Term Storage: -20°C
Use/Stability: Stock solutions are stable for up to 3 months when stored at -20°C.
Handling: Protect from light. Hygroscopic. |