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PTH, human recombinant
A hormone regulating serum calcium
Product Overview
Alternate Names / Synonyms: Human PTH, PTH, h-PTH, rh-PTH, recombinant human PTH, PTH, recombinant PTH
Gene Symbol: PTH
Accession #: P01270
Gene ID: 5741
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized powder
Molecular Weight: 9.0 kDa
Purity by SDS-PAGE: N/A
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Recombinant human PTH is fully active when compared to standards. The activity calcμlated by μmR10⁶ cells/cAMP method corresponds to a specific activity of 1 x 10⁴ IU/mg.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Parathyroid Hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extraCellular fluid. This hormone is secreted from cells of the parathyroid glands and targets cells in bone and kidney. Like other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intraCellular processing, the mature hormone is packaged within the Golgi into secretary vesicles and secreted into blood by exocytosis. Recombinant human PTH is a 9 kDa protein consisting of 84 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |