Human Galectin-1

Galectin-1, human recombinant
Modulates cell–cell and cell–matrix interactions
Product Overview
Alternate Names / Synonyms: Human Galectin-1, Galectin-1, Galectin1, Galectin 1, h-Galectin-1, rh-Galectin-1, recombinant human Galectin-1, Galectin, recombinant Galectin-1
Gene Symbol: LGALS1
Accession #: P09382
Gene ID: 3956
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 20 mM Tris, pH 7.5.
Molecular Weight: 14.5 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Galectin-1 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of β-galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds β-galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.