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BMP-13, human recombinant
A TGF-beta family protein involved in patterning of the epidermis and bone & joint formation
Product Overview
Alternate Names / Synonyms: Human BMP-13, BMP-13, BMP13, BMP 13, h-BMP-13, rh-BMP-13, recombinant human BMP-13, recombinant BMP-13, BMP
Gene Symbol: GDF6
Accession #: Q6KF10
Gene ID: 392255
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 27 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3 µg/ml.
Reconstitution Instructions: Reconstitute to 0.1-1.0 mg/ml in water containing BSA (50 μg BSA per 1 μg of protein).
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-b superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. BioVision’s recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |