Ficolin-1 Antibody
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Product OverviewAntibody Target: Ficolin-1
Alternative Name: Flow cytometryN1 , Flow cytometryNM , ficolin 1
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 320 of rat Ficolin-1
Accession#: Q9WTS8
Gene ID: 83517
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa Ficolin-1 and a 37 kDa Ficolin-1 precursor in samples from human, mouse and rat origins. Reactivity to other species has not been tested.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Ficolin-1 also known as M-Ficolin is a pattern recognition molecule of the lectin complement activation pathway. It is expressed mostly in monocytes, nuetrophils and in type II alveolar epithelial cells. Ficolin-1 is detected on the surface of circulating monocytes but is not present in the plasma. Ficolin-1 has a 28 aa signal sequence, an N-terminal collagen domain and a C-terminal fibrinogen-like (FBG) domain that contain a calcium binding site and a potential N-glycosylation site.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans.
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