Brk Antibody
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Product OverviewAntibody Target: Brk
Alternative Name: BRK, FLJ42088 , PTK6 , breast tumor kinase
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk
Accession#: EAW75262
Gene ID: 5753
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Brk polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~57 kDa Brk of human, mouse, and rat origins. Reactivity to other species has not been tested.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Breast tumor kinase, Brk (also known as PTK6), is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans.
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