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CCR4 Antibody
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Product OverviewAntibody Target: CCR
Alternative Name: C-C chemokine receptor 4, CCR 4, chemokine C C motif receptor 4 , C-C CKR-4, K5-5
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 32 of human CCR4
Accession#: 232680
Gene ID: 1233
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, dog
Application: Western blot
Application & Usage: Western blotting (2-6 µg/ml). However, the optimal concentrations should be determined individually.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans.
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