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MAP-1 (Modulator of Apoptosis-1) Antibody
Product Overview
Antibody Target: MAP-1 (Modulator of Apoptosis-1)
Alternative Name: MAP1 , MAP1A , MAP1L , MTAP1A , FLJ77111
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding a.a. 342 of mouse MAP-1 (Modulator of Apoptosis-1)
Accession#: Q9ERH6
Gene ID: 64113
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) Protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse
Application: Western blot
Application & Usage: Western blotting (1-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate (Cat.# 2401-100) and mouse small intestine tissue lysate (Cat.# 2601-100) can be used as positive controls. The antibody recognizes 39 kDa MAP-1 from samples of human, mouse and rat origins. Reactivity to other species has not been determined. In human samples, an additional ~78 kDa dimer can be detected in Jurkat cell lysate. In mouse sample, an additional ~33 kDa cleavage fragment can also be detected in mouse small intestine tissue lysate.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Human MAP-1 (Modulator of Apoptosis Protein) is a novel Bax-associating protein. MAP-1 mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-XL of the Bcl-2 family.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |