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SGLT-2 Antibody
Product Overview
Antibody Target: SGLT-2
Alternative Name: SGLT 2 , SGLT2 , SLC5A2 ,SLC5A 2 ,
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide near the N-terminus of mouse SGLT-2
Accession#: Q923I7
Gene ID: 246787
Appearance: Colorless liquid
Concentration: 0.2 mg/ml
Formulation: 100 µg (0.2 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been determined. The antibody detects 74 kDa SGLT-2 from human, mouse, and rat origins. Reactivity to other species has not been determined. A ~55 kDa and a ~45 kDa bands can also been detected, representing the SGLT-2 cleavage fragments.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Sodium glucose co transporters (SGLTs) are located in the brush-border membrane, but transported out of the cell across the basolateral membranes by a facilitated sugar transporter (GLUT). At least three members of SGLTs (SGLT 1-3) have been cloned and characterized. SGLTs transport a methyl-D-glucoside (a-MDG), a non-metabolized model substrate, in Na-dependent manner. SGLT-1 does not discriminate a-MDG, glucose, and galactose. SGLT2/3 do not transport D-galactose efficiently.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |