TEM-8/ATR1 Antibody
Product Overview
Antibody Target: TEM-8
Alternative Name: Tumor Endothelial Marker 8 , TEM-8, TEM8 , ATR , FLJ10601 , FLJ11298 , FLJ21776
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 484 of Mouse TEM8
Accession#: AAL11999
Gene ID: 69538
Appearance: Colorless liquid
Concentration: 0.2 mg/ml
Formulation: 100 µg (0.2mg/ml) affinity purified rabbit anti-TEM8/ATR1 polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~80-85 kDa doublet of TME8 in samples from human, mouse and rat origins. Reactivity to other species has not been tested.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Tumor Endothelial Markers (TEMs, TEM 1-9) are recently identified genes, whose expression is elevated in tumor-associated endothelium. TEMs are barely detectable in normal endothelial cells. TEM8 has been shown to interact with C5 domain of collagen a3(VI), a protein also preferentially expressed in tumor endothelium. It is thought that TEM8 may play a role in tumor angiogenesis.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |