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Camptothecin (2 mM)
Product Overview
Product Name: Camptothecin (2 mM)
Alternate Name/Synonyms: (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
Description: Reversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat, osteosarcoma and hepatoma cells.
Peptide Sequence: N/A
Appearance: Liquid
Formulation: DMSO ( 2 mM)
CAS Number: 2114454
Molecular Formula: C₂₀H₁₆N₂O₄
Molecular Weight: 348.4
Purity: >98% by TLC
Solubility:N/A
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
InChi: InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
InChi Key: VSJKWCGYPAHWDS-FQEVSTJZSA-N
PubChem CID: 24360
MDL Number: MFCD00081076
USAGE: For Research Use Only! Not For Use in Humans. |