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N-butyryl-L-Homocysteine thiolactone Exclusive
Cayman Chemical Item Number 10011204
Description Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, the small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism.1↗ N-butyryl-L-Homocysteine thio-lactone induces violacein expression in C. violaceum mutants usually not able to produce AHLs.1↗,2↗
Formal Name N-[(3S)-tetrahydro-2-oxo-3-thienyl]-butanamide
CAS Number 202284-85-3
Molecular Formula C8H13NO2S
Formula Weight 187.3
Formulation A crystalline solid
Purity ≥95%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES CCCC(=O)N[C@H]1CCSC1=O
InCHI Code 1S/C8H13NO2S/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)/t6-/m0/s1
InCHI Key IMJUOGHALGXOSS-LURJTMIESA-N |