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anti-mouse CD14 FITC Sa2-8 50 ug
Anti-Mouse CD14 FITC
Also known as: LPS-R, Mo2
Clone: Sa2-8
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 11-0141
Description: The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55 kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation). |