anti-mouse CD4 FITC GK1.5 50 ug Anti-Mouse CD4 FITC Also known as: L3T4, Ly-4 Clone: GK1.5 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 11-0041 Description: The GK1.5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of GK1.5 is blocked by RM4-5. |