Functional Aspects:Dystrophin is a rod-like cytoskeletal protein found adjacent to the muscle membrane. It is one component of a complex system that links actin on the inside of muscle fibers to extracellular matrix proteins that surround the fibers. Mutations in the genes that encode for dystrophin lead to altered expression of this protein and cause muscular dystrophy. This antibody will help detect dystrophin in normal tissue sections.