Functional Aspects:CD4 is a transmembrane glycoprotein expressed on a defined T cell subset (helper/inducer cells). Interestingly most cutaneous T cell lymphomas have been reported to have CD4 positive cells. This antibody will help identify CD expression in uncharacterized tissues.CD8 is expressed on a T cell subset of normal cytotoxic/ suppressor cells. It is also found on Natural Killer cells, and some thymocytes, peripheral blood null cells and bone marrow cells. This antibody will help detect CD8 expression on uncharacterized tissues.