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TCR alpha Antibody
Product Overview
Antibody Target: TCR alpha
Alternative Name: T cell antigen receptor, T cell receptor alpha, TCRA, TCRD
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 138 of human TCRα
Accession#: 18195
Gene ID: 171558
Appearance: Colorless liquid
Concentration: 0.2 mg/ml
Formulation: 100 mg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human
Application: Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage: The antibody can be used in Western blotting (0.5-4 mg/ml). Based on researcher’s feedback, it can also be used in immunoprecipitation (10-20 mg/ml); and immunohistochemistry (15-25 mg/ml). However, the optimal concentrations should be determined individually.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either α and β or γ and δ chains. The vast majority of circulating T cells (95%) express the α/β heterodimer while roughly 2-5% express the γ/δ heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |