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LIGHT Antibody
Product Overview
Antibody Target: LIGHT
Alternative Name: Tumor necrosis factor ligand, TNF14, TNF 14, TNF-14
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Recombinant human LIGHT
Accession#: AAC39563
Gene ID: 8740
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) antigen affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification: Affinity purified
Species Reactivity: human
Application: Western blot
Application & Usage: Western blotting (0.5-1 µg/ml). However, the optimal conditions should be determined individually. The antibody detects human LIGHT. Reactivity to other species has not been tested.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |