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IL-21R Antibody
Product Overview
Antibody Target: IL-21R
Alternative Name: IL-21, IL21R, IL 21R, Interluekin-21R, Interleukin 21R, interluekin21R
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide corresponding to amino acids 20-32 of human IL-21R precursor
Accession#: NP_068570
Gene ID: 50615
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity-purified rabbit anti-human IL-21R polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification: Affinity purified
Species Reactivity: human
Application: Western blot
Application & Usage: Western blot analysis (1 µg/ml). However, the optimal conditions should be determined individually. Human A431 cell lysates can be used as a positive control and an approximately 60 kDa band should be detected.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: IL-21 is a novel cytokine that was recently identified in human and mouse. It has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel interleukin receptor) is a new member of the class I cytokine receptor family. IL-021R forms a complex with the common cytokine receptor g chain and mediates IL-21 signaling. IL-21 and its receptor activates JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, HL-60, and THP-1 cell lines. IL-21 plays an important role in the proliferation and maturation of NK, B and T cell populations.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |