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C3aR Antibody
Product Overview
Antibody Target: C3aR
Alternative Name: C3a receptor-like, C3a anaphylatoxin chemotactic receptor, C3a anaphylatoxin chemotactic, C3a-R, C3AR
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: E. coli expressed human C3aR (a.a. 161-332)
Accession#: Q16581
Gene ID: 719
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification: Affinity purified
Species Reactivity: human
Application: Flow cytometry
Application & Usage: The antibody recognizes C3aR expressed in leukocytes and in transfected cells using flow cytometry.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: C3a is an anaphylatoxin generated through activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains. The loop can be readily detected using the rabbit anti-C3a receptor antibody.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |