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SDF-1alpha Antibody
Product Overview
Antibody Target: SDF-1a
Alternative Name: SDF-1a, SDF 1a, SDF 1alpha, SDF 1 alpha, SDF -1, SDF, Stromal cell-derived factor 1;DF-1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; PBSF;SDF-1-alpha
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: E. coli-expressed human SDF-1α
Accession#: NP_001029058
Gene ID: 6387
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-human SDF-1α polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01 thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat
Application: Western blot
Application & Usage: Western blot analysis (0.5-1 µg/ml). Based on researcher’s feedback, it can also be used in immunofluorescence and neutralization (2-10 µg/ml). However, the optimal conditions should be determined individually.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: SDF-1α (stromal cell-derived factor-α), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |