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RANTES Antibody
Product Overview
Antibody Target: RANTES
Alternative Name: Chemokine, CC motif, ligand 5, CCL5, CCL-5, CCL 5
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: E. coli-expressed mature rat RANTES (a.a. 1-70)
Accession#: NP_112378
Gene ID: 81780
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-RANTES polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification: Affinity purified
Species Reactivity: mouse, rat
Application: Western blot
Application & Usage: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. RAW264.7 cells treated with LPS (15 hr) can be used as a positive control.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T-cell-specific sequences-enriched cDNA libraries. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T-cells and eosinophils, as well as an activator of basophils for histamine release. In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |